David Sinclair on the Joe Rogan Experience Podcast
QUALITY OF OUR PRODUCTS
Rest assured! All our products are made in a GMP (Good Manufacturing Practice) and FDA certified facility. What does this mean?
What is GMP?
GMP refers to the Good Manufacturing Practice regulations enforced by the FDA. GMPs provide for systems that assure proper design, monitoring, and control of manufacturing processes and facilities. Adherence to the GMP regulations assures the identity, strength, quality, and purity of drug products by requiring that manufacturers of medications adequately control manufacturing operations. This includes establishing strong quality management systems, obtaining appropriate quality raw materials, establishing robust operating procedures, detecting and investigating product quality deviations, and maintaining reliable testing laboratories.
NMN48000 Enhanced N+1 Formula
$269
On the basis of technology, NMN and AMPK are divided into male and female models according to the differences in physical fitness between men and women.
3. No additives added, with a net content exceeding 48000mg
4. Due to technological upgrades in absorption rate and administration methods, it has achieved dual effect absorption of enteric and gastric dissolution without relying on tolerance, and has won the Nobel Prize in Technology.
5. Supplement NAD+to repair human cells, effectively eliminate residual damage and aging cells in the body, and increase the activity and health of existing cells. Consolidate functions, revitalize the body, prevent aging, suitable for both men and women
Five generation advantages:
1. External supplementation of endogenous regeneration, consolidation of functions, synergistic enhancement; The upgraded NMN stimulates endogenous bodily functions through external supplementation, activates the conversion and internal circulation of NAD+through multiple pathways, and achieves effective circulation and regeneration of bodily functions, elevating various bodily functions to a relatively healthy level.
2. N+1 component, releases awakening factors, targets precise absorption, assists in repairing and enhancing efficiency.
What is nmn
NMN is an entirely natural compound found in our bodies. Various food sources also contain this compound in minuscule amounts. Edamame which has one of the higher contents, only show less than 1.9mg/100g. NMN is a direct and potent NAD+ supplement. Mice given an oral supplement of NMN showed increased liver NAD+ levels in just 10 minutes and showed an increase in muscle tissue by 30 minutes.
Increased NAD+ levels stimulate energy metabolism, DNA repair, and SIRTUIN activity. SIRTUINS are the longevity-genes shown to be active during caloric restriction and life-extension in many animal models.
The science
Scientists have now confirmed a direct link between falling NAD+ levels and aging in both animals and human subjects. A breakthrough study published by Harvard scientists in 2013 showed for the first time that some aspects of aging might be reversible. After treating old mice with NMN, several biometric markers that were subsequently measured resembled those of young mice: "the equivalent of a 60-year old converting to a 20-year old". The research and understanding into NAD+ metabolomics are ongoing, but what the science has highlighted thus far, is the importance of supporting and maintaining our NAD+ levels.
A long-term evaluation of oral supplementation of NMN in mice was found to be effective at improving NAD+ levels safely. Mice supplemented with NMN vs. a control group showed notable age-associated differences in mass, energy metabolism, blood sugar, lipid metabolism, gene expression changes, mitochondrial oxygen use, eye function, bone density and immune function with no apparent toxic effects.
